Mycophenolic acid area under the curve recovery time following rifampicin withdrawal
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چکیده
منابع مشابه
Boosting the Area under the ROC Curve
We show that any weak ranker that can achieve an area under the ROC curve slightly better than 1/2 (which can be achieved by random guessing) can be efficiently boosted to achieve an area under the ROC curve arbitrarily close to 1. We further show that this boosting can be performed even in the presence of independent misclassification noise, given access to a noise-tolerant weak ranker.
متن کاملA limited sampling strategy for estimation of the area under the curve (0 to 8 hours) of mycophenolic acid administered three times daily to liver transplant recipients
OBJECTIVES Gastrointestinal side-effects caused by mycophenolic acid (MPA) are frequent in liver transplant recipients, and in these cases a switch from two to three daily doses is usually recommended. However, a limited sampling strategy for the estimation of MPA area under the curve from 0 to 8 hours (AUC(0-8h)) has not been made. DESIGN AND METHODS In 22 liver transplant patients who were ...
متن کاملLimited sampling strategy for the estimation of mycophenolic acid area under the curve in adult renal transplant patients treated with concomitant tacrolimus.
BACKGROUND Significant relationships between the mycophenolic acid (MPA) area under the concentration-time curve (AUC(0-12h)) and the risks for acute rejection and side effects have been reported. We developed a practical method for estimation of MPA AUCs. Regression equations were developed using repeated cross-validation for randomly chosen subsets, characterized statistically, and verified f...
متن کاملUsefulness of limited sampling strategy for mycophenolic acid area under the curve considering postoperative days in living-donor renal transplant recipients with concomitant prolonged-release tacrolimus
BACKGROUND The optimal dose of mycophenolate mofetil (MMF) in renal transplant patients has been recommended to be decided on the basis of area under the concentration-time curve (AUC0-12) of mycophenolic acid (MPA). Although meta-analysis has revealed that postoperative day (POD) is an influencing factor in MPA pharmacokinetics, there are no reports regarding a limited sampling strategy (LSS) ...
متن کاملEstimation of Mycophenolic Acid Area Under the Curve With Limited-Sampling Strategy in Chinese Renal Transplant Recipients Receiving Enteric-Coated Mycophenolate Sodium
BACKGROUND The enteric-coated mycophenolate sodium (EC-MPS), whose active constituent is mycophenolic acid (MPA), has been widely clinically used for organ transplant recipients. However, its absorption is delayed due to its special designed dosage form, which results in difficulty to monitor the exposure of the MPA in patients receiving the EC-MPS. This study was aimed at developing a relative...
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ژورنال
عنوان ژورنال: Indian Journal of Nephrology
سال: 2010
ISSN: 0971-4065
DOI: 10.4103/0971-4065.62091